The Hidden Dangers of Cortisone Injections for Musculoskeletal Pain

dangers of cortisone injections

Article reviewed by Dr. John L Ferrell III M.D

Cortisone injections have long been a popular treatment option for musculoskeletal pain, particularly for issues involving joints and soft tissues. However, a recent review highlights the potential adverse effects and risks associated with corticosteroid injections, shedding light on why this commonly used therapy may not be as safe as once thought.

Understanding Cortisone and Its Use in Musculoskeletal Conditions

Cortisone, a type of corticosteroid, is often injected to help reduce inflammation and provide pain relief for conditions such as bursitis, tendinitis, and rotator cuff injuries. These injections can provide short-term relief and help patients resume normal activities; however, they come with significant downsides that may outweigh the benefits for some individuals.

The recent literature review, published in the New Zealand Journal of Physiotherapy (*), discusses findings from multiple studies and databases on the adverse effects of corticosteroid injections for non-spinal musculoskeletal conditions. The authors emphasized that while corticosteroid injections can help with short-term symptom relief, they may also lead to severe local and systemic complications.

Potential Adverse Effects of Cortisone Injections

Tendon Rupture: One of the most alarming findings is the increased risk of tendon rupture. For example, rotator cuff tendons may be more susceptible to damage after cortisone injections due to suppressed tenocyte activity and collagen synthesis. Repeated cortisone injections can weaken tendons, making them prone to full-thickness tears.
Cartilage Damage: Cortisone injections can contribute to cartilage thinning and degeneration over time. In a study involving knee joints, patients who received cortisone every three months for two years showed signs of cartilage breakdown, raising concerns about the long-term impact of these injections on joint health.
Systemic Side Effects: Cortisone injections can also lead to systemic issues such as elevated blood sugar levels (particularly concerning for diabetic patients), myopathy (muscle weakness), and adrenal suppression. These effects highlight that cortisone is not just acting locally but can have widespread implications for overall health.

Is Cortisone the Best Option for You?

While cortisone injections may provide temporary pain relief, it’s essential to weigh the risks and benefits. The evidence suggests that cortisone can lead to complications that may ultimately worsen the condition it’s intended to treat. Platelet-Rich Plasma (PRP) and other regenerative therapies are emerging as safer, more effective options for treating musculoskeletal pain, as they promote healing rather than merely masking symptoms.

Seeking Safer Alternatives: The Role of Regenerative Medicine

At our clinics, we specialize in regenerative orthopedics that offer long-term solutions without the risks associated with cortisone. Our PRP treatments use your body’s natural healing processes to reduce pain, promote tissue repair, and avoid the adverse side effects linked to corticosteroids. If you’re struggling with chronic joint or tendon pain, consider exploring PRP or micro-fragmented adipose tissue (MFAT) as a safer and more effective alternative to cortisone injections.

Ready to Find a Better Solution?

If you’re interested in learning more about how regenerative medicine can help you avoid the potential downsides of cortisone injections, contact us today. Our experienced team is ready to help you get back to an active, pain-free lifestyle with treatments designed to heal, not just mask the pain.

Written by Colin Potts